SAFETY DATA SHEET
Glutaraldehyde 2% Fixative in 0.1M Phosphate Buffer, pH 7.4
1. IDENTIFICATION
Product Identifiers
Product Name:
Glutaraldehyde (2%) Fixative in 0.1M Phosphate Buffer, pH 7.4
Other Names:
Nil
Product Number(s):
16536-05, 16536-05-2MLCR, 16536-05-SP, 16536-10, 16536-SPECIAL, C16536-05, C16536-10
CAS Number:
111-30-8
Recommended use of the chemical and restriction on use
For research and laboratory use only.
Company Details
ProSciTech Pty Ltd
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
Emergency Contact Details
ProSciTech Pty Ltd
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
GHS08 Health hazard
Sensitization - respiratory 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
GHS07
Skin irritation 2 H315 Causes skin irritation.
Eye irritation 2A H319 Causes serious eye irritation.
Sensitization - skin 1 H317 May cause an allergic skin reaction.
Specific target organ toxicity (single exposure) 3 H335 May cause respiratory irritation.
Sensitization - respiratory 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
GHS07
Skin irritation 2 H315 Causes skin irritation.
Eye irritation 2A H319 Causes serious eye irritation.
Sensitization - skin 1 H317 May cause an allergic skin reaction.
Specific target organ toxicity (single exposure) 3 H335 May cause respiratory irritation.
Label Elements
Signal Words
Danger
Hazard Statement(s)
Causes skin irritation.
Causes serious eye irritation.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause an allergic skin reaction.
May cause respiratory irritation.
Causes serious eye irritation.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause an allergic skin reaction.
May cause respiratory irritation.
Precautionary Statement(s)
Avoid breathing dust/fume/gas/mist/vapours/spray
Wash thoroughly after handling.
Use only outdoors or in a well-ventilated area.
Contaminated work clothing must not be allowed out of the workplace.
Wear protective gloves / eye protection / face protection.
[In case of inadequate ventilation] wear respiratory protection.
Wash thoroughly after handling.
Use only outdoors or in a well-ventilated area.
Contaminated work clothing must not be allowed out of the workplace.
Wear protective gloves / eye protection / face protection.
[In case of inadequate ventilation] wear respiratory protection.
Primary route(s) of entry
No information available.
Human Health
Inhalation:
Remove person to fresh air and keep comfortable for breathing.
If experiencing respiratory symptoms: Call a poison center/doctor.
If experiencing respiratory symptoms: Call a poison center/doctor.
Ingestion:
No information available.
Eyes:
Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing.
Call a poison center/doctor if you feel unwell.
If eye irritation persists: Get medical advice/attention.
Continue rinsing.
Call a poison center/doctor if you feel unwell.
If eye irritation persists: Get medical advice/attention.
Skin:
Wash with plenty of water.
Take off contaminated clothing and wash it before reuse.
If skin irritation or rash occurs: Get medical advice/attention.
Take off contaminated clothing and wash it before reuse.
If skin irritation or rash occurs: Get medical advice/attention.
Environment
Dispose of contents/container to an approved waste disposal plant.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Name
CAS No.
Content (w/w)
Classification
Glutaraldehyde
111-30-8
1-5%
Flam. Liq. 4; Acute Tox., Oral 3; Acute Tox., Inhal. 2; Skin Corr. 1B; Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1B; STOT SE 3; Aquatic Acute 1; H227, H301, H314, H317, H318, H330, H334, H335, H400.
4. FIRST AID MEASURES
Ingestion
If symptoms persist consult doctor.
Inhalation
Supply fresh air and to be sure call for a doctor.
In case of unconsciousness place patient stably in side position for transportation.
In case of unconsciousness place patient stably in side position for transportation.
Skin Contact
Immediately wash with water and soap and rinse thoroughly.
Eye Contact
Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.
Other Information
Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.
5. FIREFIGHTING MEASURES
Suitable extinguishing equipment
Use fire fighting measures that suit the environment. Water spray, alcohol-resistant foam, dry chemical, and carbon dioxide extinguishers are suitable.
HAZCHEM
No further relevant information available.
Special protective equipment and precautions for fire fighters
6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Provide suitable ventilation. Use any necessary personal protective equipment. Avoid contact with skin and eyes, and avoid creation and inhalation of vapour or dust. Keep all unnecessary personnel away.
Environmental precautions
Prevent product from entering public sewers and waterways.
Methods and materials for containment and clean up
Use inert absorbent material to absorb any spilled or leaked product and dispose of as hazardous waste. Keep in suitable, closed containers for disposal.
7. HANDLING AND STORAGE
Precautions for safe handling
Ensure good ventilation/exhaustion at the workplace.
Prevent formation of aerosols.
Prevent formation of aerosols.
Conditions for safe storage
· Information about storage in one common storage facility: Not required.
· Further information about storage conditions: Keep receptacle tightly sealed.
· Specific end use(s) No further relevant information available.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Standards
Material
TWA ppm
TWA mg/m3
STEL ppm
STEL mg/m3
Glutaraldehyde
0.2 ppm
0.8 mg/m³
-
Engineering controls
Follow good industrial hygiene and safety practices when handling product.
Personal protective equipment
Eye and face protection
Use only government-approved safety glasses with side-shields.
Skin protection
Use gloves when handling product. Inspect gloves before use to ensure suitability for use. Remove without exposing skin to the gloves outer surface. Discard used gloves according to all pertinent laws and/or current good practices (cGXP). Wash hands with soap and water.
Body protection
Wear appropriate clothing. Ensure clothing is in good condition, with no holes or tears. When selecting clothing, consider the concentration and amount of substance to be handled.
Respiratory protection
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air
9. PHYSICAL AND CHEMICAL PROPERTIES
General information
Appearance
Colourless to light yellow liquid
Odour
Characteristic
pH
7.4
Vapour Pressure
Not available
Density
Not available
Boiling Point
100 °C (212 °F)
Melting Point
0 °C (32 °F)
Solubility
Fully miscible
Specific Gravity of Density
Not available
Flash Point
Not available
Flammable (Explosive) Limits
Not available
Ignition Temperature
Not available
Formula
C₅H₈O₂, Structural (condensed) formula: OHC-(CH₂)₃-CHO
10. STABILITY AND REACTIVITY
Reactivity
No special reactivity is known.
Chemical stability
Product is stable when stored and used as recommended.
Possibility of hazardous reactions
Carbon oxides may be released under fire conditions.
Conditions to avoid
No further relevant information available
Incompatible materials
No further relevant information available
11. TOXICOLOGICAL INFORMATION
Acute effects
Sensitization possible through inhalation.
Sensitization possible through skin contact
Sensitization possible through skin contact
Eye contact
Irritanting effect.
Skin contact
Irritant to skin and mucous membranes.
Ingestion
No information available
Inhalation
No information available
Toxicity and irritation
Carcinogenic categories
· IARC (International Agency for Research on Cancer): None of the ingredients is listed.
· NTP (National Toxicology Program): None of the ingredients is listed.
· OSHA-Ca (Occupational Safety Health Administration): None of the ingredients is listed.
· IARC (International Agency for Research on Cancer): None of the ingredients is listed.
· NTP (National Toxicology Program): None of the ingredients is listed.
· OSHA-Ca (Occupational Safety Health Administration): None of the ingredients is listed.
12. ECOLOGICAL INFORMATION
Ecotoxicity
No further relevant information available.
Persistence and degradability
No further relevant information available.
Bioaccumulative potential
No further relevant information available.
Other adverse effects
Harmful to fish
· Additional ecological information:
· General notes:
Water hazard class 2 (Self-assessment): hazardous for water
Do not allow product to reach ground water, water course or sewage system.
Danger to drinking water if even small quantities leak into the ground.
Harmful to aquatic organisms
· Additional ecological information:
· General notes:
Water hazard class 2 (Self-assessment): hazardous for water
Do not allow product to reach ground water, water course or sewage system.
Danger to drinking water if even small quantities leak into the ground.
Harmful to aquatic organisms
13. DISPOSAL CONSIDERATIONS
General information
Waste treatment methods
· Recommendation:
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
· Uncleaned packagings:
· Recommendation: Disposal must be made according to official regulations.
· Recommended cleansing agent: Water, if necessary with cleansing agents.
· Recommendation:
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
· Uncleaned packagings:
· Recommendation: Disposal must be made according to official regulations.
· Recommended cleansing agent: Water, if necessary with cleansing agents.
14. TRANSPORT INFORMATION
ADG label required
HAZCHEM
No further relevant information available.
UN Number
Void
Proper shipping name
Void
Transport hazard class
Void
Packing group
Void
Environmental hazard
Not applicable.
Special precautions for users
Not applicable.
Additional information
Not applicable.
15. REGULATORY INFORMATION
Poisons Schedule Number
Other Information
Sara
· Section 355 (extremely hazardous substances): None of the ingredients is listed.
· Section 313 (Specific toxic chemical listings): None of the ingredients is listed.
· TSCA (Toxic Substances Control Act):
7732-18-5 Deionised Water, Reagent Grade A.C.S. ACTIVE
111-30-8 Glutaraldehyde ACTIVE
· Hazardous Air Pollutants
None of the ingredients is listed.
Proposition 65
· Chemicals known to cause cancer: None of the ingredients is listed.
· Chemicals known to cause reproductive toxicity for females: None of the ingredients is listed.
· Chemicals known to cause reproductive toxicity for males: None of the ingredients is listed.
· Chemicals known to cause developmental toxicity: None of the ingredients is listed.
Carcinogenic categories
· EPA (Environmental Protection Agency): None of the ingredients is listed.
· TLV (Threshold Limit Value): 111-30-8 Glutaraldehyde A4
· NIOSH-Ca (National Institute for Occupational Safety and Health): None of the ingredients is listed.
· Section 355 (extremely hazardous substances): None of the ingredients is listed.
· Section 313 (Specific toxic chemical listings): None of the ingredients is listed.
· TSCA (Toxic Substances Control Act):
7732-18-5 Deionised Water, Reagent Grade A.C.S. ACTIVE
111-30-8 Glutaraldehyde ACTIVE
· Hazardous Air Pollutants
None of the ingredients is listed.
Proposition 65
· Chemicals known to cause cancer: None of the ingredients is listed.
· Chemicals known to cause reproductive toxicity for females: None of the ingredients is listed.
· Chemicals known to cause reproductive toxicity for males: None of the ingredients is listed.
· Chemicals known to cause developmental toxicity: None of the ingredients is listed.
Carcinogenic categories
· EPA (Environmental Protection Agency): None of the ingredients is listed.
· TLV (Threshold Limit Value): 111-30-8 Glutaraldehyde A4
· NIOSH-Ca (National Institute for Occupational Safety and Health): None of the ingredients is listed.
16. OTHER INFORMATION
SDS preparation date
14 January 2026
Comments
Abbreviations and acronyms:
ADR: Accord relatif au transport international des marchandises dangereuses par route (European Agreement Concerning the International
Carriage of Dangerous Goods by Road)
IMDG: International Maritime Code for Dangerous Goods
DOT: US Department of Transportation
IATA: International Air Transport Association
EINECS: European Inventory of Existing Commercial Chemical Substances
ELINCS: European List of Notified Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
HMIS: Hazardous Materials Identification System (USA)
VOC: Volatile Organic Compounds (USA, EU)
LC50: Lethal concentration, 50 percent
LD50: Lethal dose, 50 percent
PBT: Persistent, Bioaccumulative and Toxic
vPvB: very Persistent and very Bioaccumulative
NIOSH: National Institute for Occupational Safety
OSHA: Occupational Safety Health
TLV: Threshold Limit Value
PEL: Permissible Exposure Limit
REL: Recommended Exposure Limit
Skin irritation 2: Skin corrosion/irritation - Category 2
Eye irritation 2A: Serious eye damage/eye irritation - Category 2A
Sensitization - respiratory 1: Respiratory sensitisation - Category 1
Sensitization - skin 1: Skin sensitisation - Category 1
Specific target organ toxicity (single exposure) 3: Specific target organ toxicity (single exposure) - Category 3
ADR: Accord relatif au transport international des marchandises dangereuses par route (European Agreement Concerning the International
Carriage of Dangerous Goods by Road)
IMDG: International Maritime Code for Dangerous Goods
DOT: US Department of Transportation
IATA: International Air Transport Association
EINECS: European Inventory of Existing Commercial Chemical Substances
ELINCS: European List of Notified Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
HMIS: Hazardous Materials Identification System (USA)
VOC: Volatile Organic Compounds (USA, EU)
LC50: Lethal concentration, 50 percent
LD50: Lethal dose, 50 percent
PBT: Persistent, Bioaccumulative and Toxic
vPvB: very Persistent and very Bioaccumulative
NIOSH: National Institute for Occupational Safety
OSHA: Occupational Safety Health
TLV: Threshold Limit Value
PEL: Permissible Exposure Limit
REL: Recommended Exposure Limit
Skin irritation 2: Skin corrosion/irritation - Category 2
Eye irritation 2A: Serious eye damage/eye irritation - Category 2A
Sensitization - respiratory 1: Respiratory sensitisation - Category 1
Sensitization - skin 1: Skin sensitisation - Category 1
Specific target organ toxicity (single exposure) 3: Specific target organ toxicity (single exposure) - Category 3
References
EMS SDS Glutaraldehyde 2% Fixative in 0.1M Phosphate Buffer, pH 7.4 01/02/2025 https://www.emsdiasum.com/docs/technical/msds/16536-05.pdf
Bioworld SDS Glutaraldehyde (2%) Fixative in 0.1M Phosphate Buffer, pH 7.4 29/10/2025 https://www.bio-world.com/site/accounts/masterfiles/MSDS/MS-30400005.pdf
Bioworld SDS Glutaraldehyde (2%) Fixative in 0.1M Phosphate Buffer, pH 7.4 29/10/2025 https://www.bio-world.com/site/accounts/masterfiles/MSDS/MS-30400005.pdf
This Safety Data Sheet (SDS) has been prepared in compliance with the Preparation of Safety Data Sheets for Hazardous Chemicals Code of Practice February 2016. It is the user's responsibility to determine the suitability of this information for adoption of necessary safety precautions. The information published in this SDS has been compiled from the publications listed in Section 16: to the best of our ability and knowledge these publications are considered accurate. We reserve the right to revise Safety Data Sheets as new information becomes available. Copies may be made for non-profit use.