SAFETY DATA SHEET
Paraformaldehyde 8% Aqueous Solution, EM Grade
1. IDENTIFICATION
Product Identifiers
Product Name:
Paraformaldehyde 8% Aqueous Solution
Other Names:
N/A
Product Number(s):
157-8 (C006), 157-8-100 (C006-100), 157-8-1L, 157-8-SP
CAS Number:
30525-89-4
Recommended use of the chemical and restriction on use
Laboratory chemicals
Company Details
ProSciTech Pty Ltd
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
Emergency Contact Details
ProSciTech Pty Ltd
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
GHS08 health hazard
Respiratory sensitisation - Category 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Flammable liquids - Category 4 H227 Combustible liquid.
Respiratory sensitisation - Category 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Flammable liquids - Category 4 H227 Combustible liquid.
Label Elements
Signal Words
Danger
Hazard Statement(s)
azard Statements
H317 - May cause an allergic skin reaction
H341 - Suspected of causing genetic defects
H350 - May cause cancer
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H317 - May cause an allergic skin reaction
H341 - Suspected of causing genetic defects
H350 - May cause cancer
H315 - Causes skin irritation
H319 - Causes serious eye irritation
Precautionary Statement(s)
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or showerP305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present andeasy to do. Continue rinsing
P310 - Immediately call a POISON CENTER or doctor/physician.
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or showerP305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present andeasy to do. Continue rinsing
P310 - Immediately call a POISON CENTER or doctor/physician.
Primary route(s) of entry
Dispose of contents/container in accordance with local/regional/national/international regulations.
Human Health
Inhalation:
Not available.
Ingestion:
Not available.
Eyes:
Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Skin:
Wash with plenty of water.
If skin irritation or rash occurs: Get medical advice/ attention.
If skin irritation or rash occurs: Get medical advice/ attention.
Environment
Not available.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Name
CAS No.
Content (w/w)
Classification
Paraformaldehyde
30525-89-4
>2.5-≤10%
Acute Tox. 3 (H301)Acute Tox. 3 (H311)Acute Tox. 3 (H331)Skin Corr. 1B (H314)Eye Dam. 1 (H318)Skin Sens. 1 (H317)STOT SE 3 (H335)Muta. 2 (H341)Carc. 1B (H350)
4. FIRST AID MEASURES
Ingestion
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
Inhalation
If not breathing, give artificial respiration. Remove from exposure, lie down. Donot usemouth-to-mouth method if victim ingested or inhaled the substance; give artificial respirationwith the aid of a pocket mask equipped with a one-way valve or other proper respiratorymedical device. Call a physician immediately.
Skin Contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
Eye Contact
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
Immediate medical attention is required.
Immediate medical attention is required.
Other Information
Show this material safety data sheet to the doctor in attendance.
Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.
Causes burns by all exposure routes. May cause allergic skin reaction. Symptoms of allergic reaction may include rash, itching, swelling, trouble breathing, tinglingof thehandsand feet, dizziness, lightheadedness, chest pain, muscle pain or flushing: Ingestionmaycause gastrointestinal irritation, nausea, vomiting and diarrhea: Product is a corrosivematerial. Use of gastric lavage or emesis is contraindicated. Possible perforation of stomach or esophagus should be investigated: Ingestion causes severe swelling, severedamage to the delicate tissue and danger of perforation.
Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.
Causes burns by all exposure routes. May cause allergic skin reaction. Symptoms of allergic reaction may include rash, itching, swelling, trouble breathing, tinglingof thehandsand feet, dizziness, lightheadedness, chest pain, muscle pain or flushing: Ingestionmaycause gastrointestinal irritation, nausea, vomiting and diarrhea: Product is a corrosivematerial. Use of gastric lavage or emesis is contraindicated. Possible perforation of stomach or esophagus should be investigated: Ingestion causes severe swelling, severedamage to the delicate tissue and danger of perforation.
5. FIREFIGHTING MEASURES
Suitable extinguishing equipment
CO₂, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
HAZCHEM
Not available.
Special protective equipment and precautions for fire fighters
6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Ensure adequate ventilation. Use personal protective equipment as required. Evacuate personnel to safe areas. Keeppeopleawayfrom and upwind of spill/leak.
Environmental precautions
Dilute with plenty of water.
Do not allow to enter sewers/ surface or ground water.
Do not allow to enter sewers/ surface or ground water.
Methods and materials for containment and clean up
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Cover drains. Collect, bind, and pump off spills.
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.
Protective Action Criteria for Chemicals
PAC-1: Paraformaldehyde 2 mg/m³
· PAC-2: Paraformaldehyde 23 mg/m³
· PAC-3: Paraformaldehyde 47 mg/m³
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.
Protective Action Criteria for Chemicals
PAC-1: Paraformaldehyde 2 mg/m³
· PAC-2: Paraformaldehyde 23 mg/m³
· PAC-3: Paraformaldehyde 47 mg/m³
7. HANDLING AND STORAGE
Precautions for safe handling
Ensure good ventilation/exhaustion at the workplace.
Open and handle receptacle with care.
Prevent formation of aerosols.
Open and handle receptacle with care.
Prevent formation of aerosols.
Conditions for safe storage
· Information about storage in one common storage facility: Not required.
· Further information about storage conditions: None.
· Specific end use(s) No further relevant information available.
Storage stabilityRecommended storage temperature: 2 - 8 °C
Storage class (TRGS 510): 4.1B: Flammable solid hazardous materials
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Standards
Material
TWA ppm
TWA mg/m3
STEL ppm
STEL mg/m3
Formaldehyde
2 ppm
2.5 mg/m3
2 ppm
2.5 mg/m3
Engineering controls
Ensure that eyewash stations and safety showers are close to the workstation location. Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of processorequipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adoptedtocontrol hazardous materials at source
Personal protective equipment
Eye and face protection
Wear tightly sealed goggles.
Avoid contact with the eyes and skin.
Avoid contact with the eyes and skin.
Skin protection
Protective gloves
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the
chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
· Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of
the glove material can not be calculated in advance and has therefore to be checked prior to the application.
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the
chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
· Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and
varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of
the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Body protection
General protective and hygienic measures:
Keep away from foodstuffs, beverages and feed.Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Store protective clothing separately.
Avoid contact with the eyes and skin.
Keep away from foodstuffs, beverages and feed.Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Store protective clothing separately.
Avoid contact with the eyes and skin.
Respiratory protection
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use self-contained respiratory protective device.
9. PHYSICAL AND CHEMICAL PROPERTIES
General information
Appearance
Clear liquid
Odour
Characteristic
pH
Not determined
Vapour Pressure
at 20 °C (68 °F): 23 hPa (17.3 mm Hg)
Density
1.0188 g/cm³ at 20 °C
Boiling Point
100 °C
Melting Point
Undetermined
Solubility
Fully miscible with water
Specific Gravity of Density
Not available.
Flash Point
>60 °C (>140 °F)
Flammable (Explosive) Limits
Not flammable
Ignition Temperature
300 °C (572 °F); Product is not selfigniting
Formula
Formula : HO(CH2O)nH
Molecular weight : 30.03 g/mol
CAS-No. : 30525-89-4
EC-No. : 608-494-5
Molecular weight : 30.03 g/mol
CAS-No. : 30525-89-4
EC-No. : 608-494-5
10. STABILITY AND REACTIVITY
Reactivity
No further relevant information available.
Chemical stability
No decomposition if used according to specifications.
Possibility of hazardous reactions
No dangerous reactions known.
Conditions to avoid
No decomposition if used according to specifications.
Incompatible materials
No further relevant information available.
11. TOXICOLOGICAL INFORMATION
Acute effects
No further relevant information available.
Eye contact
Irritating effect.
Skin contact
Irritant to skin and mucous membranes.
Sensitisation possible through skin contact.
Sensitisation possible through skin contact.
Ingestion
No further relevant information available.
Inhalation
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Toxicity and irritation
Paraformaldehyde
Oral LD50 800 mg/kg (Rat)
Dermal LD50 10,000 mg/kg (rabbit)
Inhalative LC50/4 h 1,070 mg/l (Rat)
Oral LD50 800 mg/kg (Rat)
Dermal LD50 10,000 mg/kg (rabbit)
Inhalative LC50/4 h 1,070 mg/l (Rat)
12. ECOLOGICAL INFORMATION
Ecotoxicity
General notes:
Water hazard class 2 (Self-assessment): hazardous for water
Do not allow product to reach ground water, water course or sewage system.
Danger to drinking water if even small quantities leak into the ground.
Water hazard class 2 (Self-assessment): hazardous for water
Do not allow product to reach ground water, water course or sewage system.
Danger to drinking water if even small quantities leak into the ground.
Persistence and degradability
No further relevant information available.
Bioaccumulative potential
No further relevant information available.
Other adverse effects
No further relevant information available.
13. DISPOSAL CONSIDERATIONS
General information
Must not be disposed together with household garbage. Do not allow product to reach sewage system. Disposal must be made according to official regulations. Water, if necessary together with cleansing agents.
14. TRANSPORT INFORMATION
ADG label required
HAZCHEM
Not available.
UN Number
None
Proper shipping name
Not regulated.
Transport hazard class
Void
Packing group
None.
Environmental hazard
No information available.
Special precautions for users
No information available.
Additional information
No information available.
15. REGULATORY INFORMATION
Poisons Schedule Number
Not listed.
Other Information
No further relevant information available.
16. OTHER INFORMATION
SDS preparation date
9 December 2025
Comments
Abbreviations and acronyms:
ADR: Accord relatif au transport international des marchandises dangereuses par route (European Agreement Concerning the International
Carriage of Dangerous Goods by Road)
IMDG: International Maritime Code for Dangerous Goods
IATA: International Air Transport Association
EINECS: European Inventory of Existing Commercial Chemical Substances
ELINCS: European List of Notified Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
VOC: Volatile Organic Compounds (USA, EU)
PBT: Persistent, Bioaccumulative and Toxic
vPvB: very Persistent and very Bioaccumulative
Flammable liquids - Category 4: Flammable liquids - Category 4
Respiratory sensitisation - Category 1: Respiratory sensitisation - Category 1
ADR: Accord relatif au transport international des marchandises dangereuses par route (European Agreement Concerning the International
Carriage of Dangerous Goods by Road)
IMDG: International Maritime Code for Dangerous Goods
IATA: International Air Transport Association
EINECS: European Inventory of Existing Commercial Chemical Substances
ELINCS: European List of Notified Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
VOC: Volatile Organic Compounds (USA, EU)
PBT: Persistent, Bioaccumulative and Toxic
vPvB: very Persistent and very Bioaccumulative
Flammable liquids - Category 4: Flammable liquids - Category 4
Respiratory sensitisation - Category 1: Respiratory sensitisation - Category 1
References
EMS SDS PARAFORMALDEHYDE 8% AQUEOUS SOLUTION, EM GRADE 27/12/2024 https://www.emsdiasum.com/docs/technical/msds/157-8.pdf
ThermoFisher Paraformaldehyde, 8% w/v aq. soln., methanol free SDS 18/03/2024 https://documents.thermofisher.com/DirectWebViewer/private/document.aspx?prd=ALFAA47347~~PDF~~MTR~~CLP1~~EN~~2024-08-02%2013:01:33~~Paraformaldehyde%20%208%%20w/v%20aq.%20soln.%20%20methanol%20free~~
ThermoFisher Paraformaldehyde, 8% w/v aq. soln., methanol free SDS 18/03/2024 https://documents.thermofisher.com/DirectWebViewer/private/document.aspx?prd=ALFAA47347~~PDF~~MTR~~CLP1~~EN~~2024-08-02%2013:01:33~~Paraformaldehyde%20%208%%20w/v%20aq.%20soln.%20%20methanol%20free~~
This Safety Data Sheet (SDS) has been prepared in compliance with the Preparation of Safety Data Sheets for Hazardous Chemicals Code of Practice February 2016. It is the user's responsibility to determine the suitability of this information for adoption of necessary safety precautions. The information published in this SDS has been compiled from the publications listed in Section 16: to the best of our ability and knowledge these publications are considered accurate. We reserve the right to revise Safety Data Sheets as new information becomes available. Copies may be made for non-profit use.