SAFETY DATA SHEET
Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride (NMA)
1. IDENTIFICATION
Product Identifiers
Product Name:
Nadic Methyl Anhydride (NMA)
Other Names:
Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride
Product Number(s):
C046
CAS Number:
25134-21-8
Recommended use of the chemical and restriction on use
Laboratory use.
Company Details
ProSciTech Pty Ltd
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
Emergency Contact Details
ProSciTech Pty Ltd
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
GHS08 health hazard
Resp. Sens. 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
GHS07
Acute Tox. 4 H302 Harmful if swallowed.
Skin Irrit. 2 H315 Causes skin irritation.'
Eye Irrit. 2A H319 Causes serious eye irritation.
GHS05 Corrosion
Skin corrosion 1C H314 Causes severe skin burns and eye damage.
Resp. Sens. 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
GHS07
Acute Tox. 4 H302 Harmful if swallowed.
Skin Irrit. 2 H315 Causes skin irritation.'
Eye Irrit. 2A H319 Causes serious eye irritation.
GHS05 Corrosion
Skin corrosion 1C H314 Causes severe skin burns and eye damage.
Label Elements
Signal Words
Danger
Hazard Statement(s)
H302 Harmful if swallowed.
H314 Causes severe skin burns and eye damage.
H317 May cause an allergic skin reaction.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H314 Causes severe skin burns and eye damage.
H317 May cause an allergic skin reaction.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statement(s)
Prevention
P261 Avoid breathing mist or vapours.
P264 Wash skin thoroughly after handling.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P284 Wear respiratory protection.
P261 Avoid breathing mist or vapours.
P264 Wash skin thoroughly after handling.
P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
P284 Wear respiratory protection.
Primary route(s) of entry
Not available.
Human Health
Inhalation:
P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor.
Ingestion:
P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Eyes:
P305 + P351 + P338 + P310
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor.
Skin:
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
Environment
No further relevant information available.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Name
CAS No.
Content (w/w)
Classification
(Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride
25134-21-8
<= 100 %
Acute Tox. 4; Skin Corr. 1; Eye Dam. 1; Resp. Sens.1; Skin Sens. 1; H302, H314, H318, H334, H317
4. FIRST AID MEASURES
Ingestion
Call for a doctor immediately.
Inhalation
In case of unconsciousness place patient stably in side position for transportation.
Skin Contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
Eye Contact
Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.
Other Information
Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.
5. FIREFIGHTING MEASURES
Suitable extinguishing equipment
CO₂, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
HAZCHEM
Not available.
Special protective equipment and precautions for fire fighters
keeping a safe distance or by wearing suitable protective clothing.
Further information
Prevent fire extinguishing water from contaminating surface water or the ground water system
6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapours, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
For personal protection see section 8.
Environmental precautions
Do not allow to enter sewers/ surface or ground water.
Methods and materials for containment and clean up
Dispose contaminated material as waste according to item 13.
Ensure adequate ventilation.
Ensure adequate ventilation.
7. HANDLING AND STORAGE
Precautions for safe handling
Ensure good ventilation/exhaustion at the workplace.
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Conditions for safe storage
Tightly closed. Keep locked up or in an area accessible only to qualified or authorised persons.
Moisture sensitive.
Storage class
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Standards
Engineering controls
No information available.
Personal protective equipment
Eye and face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
Skin protection
Wash hands before breaks and at the end of work.
Avoid contact with the eyes and skin.
Avoid contact with the eyes and skin.
Body protection
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Immediately remove all soiled and contaminated clothing.
Respiratory protection
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use self-contained respiratory protective device.
9. PHYSICAL AND CHEMICAL PROPERTIES
General information
Appearance
Liquid
Odour
Characteristic
pH
Not determined.
Vapour Pressure
Not determined.
Density
1.232 g/cm³ (10.28104 lbs/gal)
Boiling Point
Undetermined.
Melting Point
Undetermined.
Solubility
Not determined.
Specific Gravity of Density
Not applicable.
Flash Point
135 °C (275 °F)
Flammable (Explosive) Limits
Not applicable.
Ignition Temperature
Not determined.
Formula
Not available.
10. STABILITY AND REACTIVITY
Reactivity
No further relevant information available.
Chemical stability
Not available.
Possibility of hazardous reactions
No dangerous reactions known.
Conditions to avoid
No further relevant information available.
Incompatible materials
No further relevant information available.
11. TOXICOLOGICAL INFORMATION
Acute effects
No further relevant information available.
Eye contact
Irritating effect.
Skin contact
Irritant to skin and mucous membranes.
Ingestion
No further relevant information available.
Inhalation
No further relevant information available.
Toxicity and irritation
No further relevant information available.
12. ECOLOGICAL INFORMATION
Ecotoxicity
No further relevant information available.
Persistence and degradability
No further relevant information available.
Bioaccumulative potential
No further relevant information available.
Other adverse effects
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
13. DISPOSAL CONSIDERATIONS
General information
Waste material must be disposed of in accordance with the national and local regulations.
Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
14. TRANSPORT INFORMATION
ADG label required
HAZCHEM
Not available.
UN Number
UN2810
Proper shipping name
DOT Toxic, liquids, organic, n.o.s. (NMA, (Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride))
ADR 2810 TOXIC LIQUID, ORGANIC, N.O.S. (NMA, (Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride))
IMDG, IATA TOXIC LIQUID, ORGANIC, N.O.S. (NMA, (Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride))
ADR 2810 TOXIC LIQUID, ORGANIC, N.O.S. (NMA, (Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride))
IMDG, IATA TOXIC LIQUID, ORGANIC, N.O.S. (NMA, (Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride))
Transport hazard class
6.1 Toxic substances
Packing group
PG III
Environmental hazard
No information available.
Special precautions for users
Special precautions for user Warning: Toxic substances
· Hazard identification number (Kemler code): 60
· EMS Number: F-A,S-A
· Hazard identification number (Kemler code): 60
· EMS Number: F-A,S-A
Additional information
Transport/Additional information:
DOT · Quantity limitations On passenger aircraft/rail: 60 L
On cargo aircraft only: 220 L
ADR · Excepted quantities (EQ) Code: E1
Maximum net quantity per inner packaging: 30 mL
Maximum net quantity per outer packaging: 1000 mL
IMDG · Limited quantities (LQ) 5L
· Excepted quantities (EQ) Code: E1
Maximum net quantity per inner packaging: 30 mL
Maximum net quantity per outer packaging: 1000 ml
DOT · Quantity limitations On passenger aircraft/rail: 60 L
On cargo aircraft only: 220 L
ADR · Excepted quantities (EQ) Code: E1
Maximum net quantity per inner packaging: 30 mL
Maximum net quantity per outer packaging: 1000 mL
IMDG · Limited quantities (LQ) 5L
· Excepted quantities (EQ) Code: E1
Maximum net quantity per inner packaging: 30 mL
Maximum net quantity per outer packaging: 1000 ml
15. REGULATORY INFORMATION
Poisons Schedule Number
Substance is not listed.
Other Information
No further relevant information available.
16. OTHER INFORMATION
SDS preparation date
9 December 2025
Comments
Abbreviations and acronyms:
ADR: Accord relatif au transport international des marchandises dangereuses par route (European Agreement Concerning the International
Carriage of Dangerous Goods by Road)
IMDG: International Maritime Code for Dangerous Goods
DOT: US Department of Transportation
IATA: International Air Transport Association
EINECS: European Inventory of Existing Commercial Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
HMIS: Hazardous Materials Identification System (USA)
PBT: Persistent, Bioaccumulative and Toxic
vPvB: very Persistent and very Bioaccumulative
NIOSH: National Institute for Occupational Safety
OSHA: Occupational Safety Health
TLV: Threshold Limit Value
PEL: Permissible Exposure Limit
REL: Recommended Exposure Limit
Acute toxicity - oral 4: Acute toxicity - Category 4
Skin corrosion 1C: Skin corrosion/irritation - Category 1C
Eye irritation 2A: Serious eye damage/eye irritation - Category 2A
Sensitization - respiratory 1: Respiratory sensitisation - Category 1
Specific target organ toxicity (single exposure) 3: Specific target organ toxicity (single exposure) - Category 3
ADR: Accord relatif au transport international des marchandises dangereuses par route (European Agreement Concerning the International
Carriage of Dangerous Goods by Road)
IMDG: International Maritime Code for Dangerous Goods
DOT: US Department of Transportation
IATA: International Air Transport Association
EINECS: European Inventory of Existing Commercial Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
HMIS: Hazardous Materials Identification System (USA)
PBT: Persistent, Bioaccumulative and Toxic
vPvB: very Persistent and very Bioaccumulative
NIOSH: National Institute for Occupational Safety
OSHA: Occupational Safety Health
TLV: Threshold Limit Value
PEL: Permissible Exposure Limit
REL: Recommended Exposure Limit
Acute toxicity - oral 4: Acute toxicity - Category 4
Skin corrosion 1C: Skin corrosion/irritation - Category 1C
Eye irritation 2A: Serious eye damage/eye irritation - Category 2A
Sensitization - respiratory 1: Respiratory sensitisation - Category 1
Specific target organ toxicity (single exposure) 3: Specific target organ toxicity (single exposure) - Category 3
References
EMS SDS NMA, (Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride) 01/02/2025 https://www.emsdiasum.com/docs/technical/msds/19000.pdf
Sigma-Aldrich SDS Methyl-5-norbornene-2,3-dicarboxylic anhydride 26/10/2023 https://www.sigmaaldrich.com/AU/en/sds/aldrich/235431?userType=anonymous
Sigma-Aldrich SDS Methyl-5-norbornene-2,3-dicarboxylic anhydride 26/10/2023 https://www.sigmaaldrich.com/AU/en/sds/aldrich/235431?userType=anonymous
This Safety Data Sheet (SDS) has been prepared in compliance with the Preparation of Safety Data Sheets for Hazardous Chemicals Code of Practice February 2016. It is the user's responsibility to determine the suitability of this information for adoption of necessary safety precautions. The information published in this SDS has been compiled from the publications listed in Section 16: to the best of our ability and knowledge these publications are considered accurate. We reserve the right to revise Safety Data Sheets as new information becomes available. Copies may be made for non-profit use.